Total steered out of it (6)
I believe the answer is:
addled
'out of it' is the definition.
(as in being addled by drink)
'total steered' is the wordplay.
'total' becomes 'add' (synonyms).
'steered' becomes 'led' (lead can mean to direct or steer).
'add'+'led'='ADDLED'
(Other definitions for addled that I've seen before include "Of egg, rotten and producing no chick" , "Mentally confused, muddled" , "Foolish or confused like bad egg" , "spoiled" , "Baffled - rotten" .)