Tours regularly around Naples, originally coming from Florence? (6)
I believe the answer is:
tuscan
'coming from florence?' is the definition.
(Florence is the capital of Tuscany)
'tours regularly around naples originally' is the wordplay.
'regularly' indicates alternate letters (regularly take one letter, leave next etc.).
'around' becomes 'ca' (circa).
'originally' suggests taking the first letters.
The first letter of 'naples' is 'n'.
The alternate letters of 'tours' are 'tus'.
'tus'+'ca'+'n'='TUSCAN'
(Other definitions for tuscan that I've seen before include "Of region around Florence" , "European" , "Person from Siena" , "From a central Italian region" , "Italian dialect spoken in Florence" .)