Trace the source of answer (5)
I believe the answer is:
react
'answer' is the definition.
(I know that answer is a more specific form of the action react)
'trace the source of' is the wordplay.
'the source of' indicates anagramming the letters.
'trace' with letters rearranged gives 'REACT'.
(Other definitions for react that I've seen before include "Hit back" , "Respond to a stimulus" , "Trace (anag)" , "Behave in response" , "Change chemically" .)