Tragedy of family meeting regal oddball (4,4)
I believe the answer is:
king lear
'tragedy' is the definition.
(I've seen this before)
'family meeting regal oddball' is the wordplay.
'family' becomes 'kin' (synonyms).
'meeting' is a charade indicator (letters next to each other).
'oddball' indicates anagramming the letters.
'regal' with letters rearranged gives 'glear'.
'kin'+'glear'='KING LEAR'
'of' is the link.
(Other definitions for king lear that I've seen before include "Shakespearian royal tragedy" , "Tragic Shakespeare monarch" , "Play set in medieval Britain" , "Shakespearean tragedy" , "Tragic Shakespearean monarch" .)