Translation of "let's go", heading for Torremolinos — "vamoose!" (3,4)
I believe the answer is:
get lost
'vamoose' is the definition.
(thesaurus)
'translation of let's go heading for torremolinos' is the wordplay.
'translation of' indicates anagramming the letters (I've seen this in other clues).
'heading for' says to take the initial letters.
The first letter of 'torremolinos' is 't'.
'lets'+'go'='letsgo'
'letsgo' is an anagram of 'getlos'.
'getlos'+'t'='GET LOST!'
(Other definitions for get lost that I've seen before include "Sling your hook!" , "On your way" , "without the map?" , "Go away or go astray" , "Go away! (colloq.)" .)