Travel sick coming back around Anglesey, say (4)
I believe the answer is:
isle
'anglesey say' is the definition.
(I know that Anglesey is a island)
'travel sick coming back around' is the wordplay.
'around' indicates a hidden word.
'coming back' is a reversal indicator.
'elsi' is hidden in the letters of 'travel sick'.
'elsi' reversed gives 'ISLE'.
(Other definitions for isle that I've seen before include "Could be Man" , "Detached place" , "Small seabound place" , "Detached territory" , "9 ac perhaps" .)