Tries again with a large drill (9)
I believe the answer is:
rehearsal
'drill' is the definition.
(rehearsal is a kind of drill)
'tries again with a large' is the wordplay.
'tries again' becomes 'rehears' ('hears' can be a synonym for 'tries' so perhaps 'rehears' is OK for 'tries again').
'with' is a charade indicator (letters next to each other).
'large' becomes 'l'.
'rehears'+'a'+'l'='REHEARSAL'
(Other definitions for rehearsal that I've seen before include "Drill" , "show trial" , "Play run-through" , "Practice - run-through" , "preparation in house?" .)