Trouble at University getting fixed (5)
I believe the answer is:
upset
'trouble' is the definition.
('upset' can be a synonym of 'trouble')
'at university getting fixed' is the wordplay.
'at university' becomes 'up'.
'getting' means one lot of letters go next to another.
'fixed' becomes 'set' ('set' can be a synonym of 'fixed').
'up'+'set'='UPSET'
(Other definitions for upset that I've seen before include "Surprise win" , "unexpectedly beaten?" , "Knock over; worried" , "Unhappy or worried state of mind" , "Pet us (anag)" .)