Trouble from Italian blocking a door (7)
I believe the answer is:
agitate
'trouble' is the definition.
(agitating is a kind of troubling)
'italian blocking a door' is the wordplay.
'italian' becomes 'it' (abbreviation for Italian).
'blocking' means one lot of letters goes inside another.
'door' becomes 'gate'.
'a'+'gate'='agate'
'it' going within 'agate' is 'AGITATE'.
'from' acts as a link.
(Other definitions for agitate that I've seen before include "Stir; tie a tag (anag.)" , "Stir violently" , "Trouble, make nervous" , "Get upset" , "Make nervous; stir" .)