Trouble, incommode (13)
I believe the answer is:
inconvenience
This clue is a double definition.
'trouble' is the first definition.
(I know that trouble can be written as inconvenience)
'incommode' is the second definition.
(synonyms)
(Other definitions for inconvenience that I've seen before include "Fag" , "Slight difficulty" , "Bother" , "Put out" , "Cause trouble (to)" .)