Try to block drop of rain with plug (6)
I believe the answer is:
spigot
'plug' is the definition.
(I know that spigot is a type of plug)
'try to block drop of rain' is the wordplay.
I cannot quite understand how this works, but
'try' could be 'go' (both can mean an attempt) and 'go' is located in the answer.
'rain' could be 'spit' (spitting is a kind of raining) and 'spit' is present in the leftover letters.
No letters remain.
This explanation may well be incorrect...
'with' acts as a link.
Can you help me to learn more?
(Other definitions for spigot that I've seen before include "Peg to control the flow of a tap" , "Small plug for cask" , "Vent hole peg - US tap" , "One stops" , "Cask stopper" .)