Tuna-mad relative (4)
I believe the answer is:
aunt
'relative' is the definition.
(aunt is a type of relative)
'tuna-mad' is the wordplay.
'mad' indicates an anagram.
'tuna' is an anagram of 'AUNT'.
(Other definitions for aunt that I've seen before include "Parent's female sibling" , "Female relative" , "Sister of father/mother" , "Parent's sister" , "Tuna (anag.)" .)