Tune from duo without piano (3)
I believe the answer is:
air
'tune' is the definition.
(air can mean a piece of music)
'duo without piano' is the wordplay.
'duo' becomes 'pair' (synonyms).
'without' indicates named letters should be taken away.
'piano' becomes 'p' (musical abbreviation).
'pair' with 'p' taken away is 'AIR'.
'from' is the link.
(Other definitions for air that I've seen before include "Lay" , "Element; tune" , "Tune - mood - atmosphere" , "Broadcast; mien" , "An impressive manner or tune" .)