Turn on setter maybe keeping a low profile! (5)
I believe the answer is:
doggo
'keeping a low profile' is the definition.
(to lie doggo is to hide out)
'turn on setter' is the wordplay.
'turn' becomes 'go' (a person's move in a board game).
'on' is a charade indicator (letters next to each other).
'setter' becomes 'dog' (a setter is a type of dog).
'go' after 'dog' is 'DOGGO'.
'maybe' is the link.
(Other definitions for doggo that I've seen before include "keeping mum out of the picture?" , "out of sight" , "lying low" , "Quietly hidden" , "(Lie) concealed" .)