Crossword Genius

Twist in extremely degenerate shape (6)

Ross

I believe the answer is:

deform

'twist' is the definition.
(deforming is a kind of twisting)

'extremely degenerate shape' is the wordplay.
'extremely' means to remove the middle letters.
'shape' becomes 'form' (synonyms).
'degenerate' with its centre taken out is 'de'.
'de'+'form'='DEFORM'

'in' is the link.

(Other definitions for deform that I've seen before include "buckle" , "Put out of shape" , "Misshape" , "Change the shape of" , "Damage" .)

I've seen this clue in the Sydney Morning Herald.
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