Twist in tornado? (4)
I believe the answer is:
wind
I believe this clue is a double definition.
'twist' is the first definition.
(I know that twist can be written as wind)
'tornado?' is the second definition.
(a tornado is a vortex of wind)
'in' acts as a link.
(Other definitions for wind that I've seen before include "take course that's not straightforward? Doesn't sound like it" , "See 23" , "Mistral, for example, or sirocco" , "Move on a twisting path" , "Breeze; meaningless talk" .)