Twisted by a twin boy (6)
I believe the answer is:
twined
'twisted' is the definition.
(twining is a kind of twisting)
'by a twin boy' is the wordplay.
'by' is a charade indicator (letters next to each other).
'boy' becomes 'Ed' (short for Edward).
'twin' next to 'ed' is 'TWINED'.
(Other definitions for twined that I've seen before include "Wound" , "Wrapped around or coiled" , "Wrapped around like string" , "Interlaced" .)