Two males in each classic work (4)
I believe the answer is:
emma
'classic work' is the definition.
(I've seen this before)
'two males in each' is the wordplay.
'two males' means two replacements for 'male'.
'male' becomes 'm' (common abbreviation).
'male' becomes 'm' (common abbreviation).
'in' indicates putting letters inside.
'each' becomes 'ea' (abbreviation).
'm'+'m'='mm'
'mm' inserted into 'ea' is 'EMMA'.
(Other definitions for emma that I've seen before include "Novel by June Austen" , "Lady Hamilton or Lady Thompson?" , "Lady - Hamilton, Nelson-s mistress" , "Name of Nelson's Lady Hamilton" , "Titled heroine" .)