Two sent off outside ark for renewed creation (4,2,3)
I believe the answer is:
work of art
'creation' is the definition.
(work of art is a kind of creation)
'two sent off outside ark for renewed' is the wordplay.
'sent off' indicates anagramming the letters.
'outside' indicates putting letters inside.
'renewed' indicates an anagram.
'two' anagrammed gives 'wot'.
'ark'+'for'='arkfor'
'arkfor' with letters rearranged gives 'rkofar'.
'wot' enclosing 'rkofar' is 'WORK OF ART'.
(Other definitions for work of art that I've seen before include "tour de force?" , "Oil, perhaps" , "Tatum" , "A fine building, picture, book etc - aesthetic labour" , "skilful achievement" .)