Two try to contain male tantrum and complaint (8)
I believe the answer is:
impetigo
'complaint' is the definition.
(impetigo is a kind of health problem)
'two try to contain male tantrum' is the wordplay.
'two' becomes 'II' (Roman numerals).
'try' becomes 'go' (both can mean an attempt).
'to contain' means one lot of letters goes inside another.
'male' becomes 'm' (common abbreviation).
'tantrum' becomes 'pet'.
'ii'+'go'='iigo'
'm'+'pet'='mpet'
'iigo' placed around 'mpet' is 'IMPETIGO'.
'and' is the link.
(Other definitions for impetigo that I've seen before include "Contagious skin infection common in children" , "Contagious skin disease with crusty spots" , "Skin condition" , "Contagious skin disease causing spots and yellow crusts" , "complaint" .)