Two ways to overcome resistance fast (6)
I believe the answer is:
starve
'fast' is the definition.
(to fast is to refrain from eating food)
'two ways to overcome resistance' is the wordplay.
'two ways' means two substitutions for 'way'.
'way' becomes 'st' (abbreviation for street).
'way' becomes 'e' (Compass direction - East).
'to' means one lot of letters go next to another (I've seen this in other clues).
'overcome resistance' becomes 'arv' (I am not sure about this - if you are sure you should believe this answer much more).
'e' after 'arv' is 'arve'.
'st'+'arve'='STARVE'
Can you help me to learn more?
(Other definitions for starve that I've seen before include "Suffer great hunger" , "Stop feeding" , "Suffer from want of food" , "Averts (anag)" , "Fail to take in" .)