Ultimately saddled with university restrictions and obligations (6)
I believe the answer is:
duties
'obligations' is the definition.
('duty' can be a synonym of 'obligation')
'ultimately saddled with university restrictions' is the wordplay.
'ultimately' suggests the final letters.
'with' means one lot of letters go next to another.
'university' becomes 'u' (abbreviation for university).
'restrictions' becomes 'ties'.
The final letter of 'saddled' is 'd'.
'd'+'u'+'ties'='DUTIES'
'and' acts as a link.
(Other definitions for duties that I've seen before include "Tasks to be done" , "Moral or legal obligations" , "Tasks; obligations" , "'Obligations, responsibilities (6)'" , "levies" .)