Uncanny, Dot (single) making right move twice in highly-strung state (5)
I believe the answer is:
wired
'in highly-strung state' is the definition.
(both can mean nervous or tense)
'uncanny dot single making right move twice' is the wordplay.
I cannot really see how this works, but
'single' could be 'i' (one) and 'i' is found within the answer.
'right' could be 'r' (common abbreviation) and 'r' is found within the answer.
The remaining letters 'wed' is a valid word which might be clued in a way I don't see.
This may be the basis of clue (or it may be nonsense).
(Other definitions for wired that I've seen before include "Nervous" , "Sent a telegram" , "Connected to an electricity supply" , "Bugged" , "Using cables; tense, edgy" .)