Uncomfortable about a tile sale (3-2-4)
I believe the answer is:
ill-at-ease
'uncomfortable' is the definition.
(being ill at ease is being uncomfortable or uneasy)
'about a tile sale' is the wordplay.
'about' is an anagram indicator.
'a'+'tile'+'sale'='atilesale'
'atilesale' anagrammed gives 'ILL-AT-EASE'.
(Other definitions for ill-at-ease that I've seen before include "Unable to relax" , "Awkward, unsure" , "Unsettled, anxious" , "Uncomfortable with a situation" , "Uneasy" .)