Uncomfortable week in a hospital room (7)
I believe the answer is:
awkward
'uncomfortable' is the definition.
(I've seen this before)
'week in a hospital room' is the wordplay.
'week' becomes 'wk' (common abbreviation).
'in' is an insertion indicator.
'hospital room' becomes 'ward' (I've seen this before).
'a'+'ward'='award'
'wk' going inside 'award' is 'AWKWARD'.
(Other definitions for awkward that I've seen before include "Clumsy - problematic" , "Clumsy and ungraceful" , "Unwieldy" , "Clumsy - difficult" , "Gauche and clumsy" .)