Understand when I seem confused about route (9)
I believe the answer is:
empathise
'understand' is the definition.
(I've seen this before)
'i seem confused about route' is the wordplay.
'confused' indicates an anagram.
'about' indicates putting letters inside.
'route' becomes 'path' (synonyms).
'i'+'seem'='iseem'
'iseem' is an anagram of 'emise'.
'emise' going around 'path' is 'EMPATHISE'.
'when' acts as a link.
(Other definitions for empathise that I've seen before include "Have fellow-feeling for" , "Be understanding of" , "Understand and feel as another person does - time phase (anag)" , "Identify mentally with another person" .)