Uneasiness, daughter is quite perturbed (8)
I believe the answer is:
disquiet
'uneasiness' is the definition.
(synonyms)
'daughter is quite perturbed' is the wordplay.
'daughter' becomes 'dis' (I've seen this in other clues).
'perturbed' indicates an anagram.
'quite' is an anagram of 'quiet'.
'dis'+'quiet'='DISQUIET'
(Other definitions for disquiet that I've seen before include "Mild anxiety" , "Uneasiness" , "Restlessness" , "Vague unease, anxiety" , "concern" .)