Unfortunate wife to look to Chuck? (6)
I believe the answer is:
wretch
'unfortunate' is the definition.
(wretch is a kind of unfortunate)
'wife to look to chuck?' is the wordplay.
I cannot quite see how this works, but
'wife' could be 'w' and 'w' is present in the answer.
'chuck?' could be 'retch' (synonyms) and 'retch' is present in the answer.
This accounts for all the letters.
This explanation may well be incorrect...
Can you help me to learn more?
(Other definitions for wretch that I've seen before include "Poor devil" , "A poor miserable person" , "Good-for-nothing" , "Swine" , "Person in pitiful circumstances" .)