Crossword Genius

Unfortunately not angelic, that’s been the case since birth (10)

Ross

I believe the answer is:

congenital

'that's been the case since birth' is the definition.
(as in a congenital health condition)

'unfortunately not angelic' is the wordplay.
'unfortunately' indicates anagramming the letters (a bad or unfortunate spelling).
'not'+'angelic'='notangelic'
'notangelic' anagrammed gives 'CONGENITAL'.

(Another definition for congenital that I've seen is " Absolute".)

I've seen this clue in The Times.
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