Unfortunately raised in Crossalaght (4)
I believe the answer is:
alas
'unfortunately' is the definition.
('alas' is used to express regret)
'raised in crossalaght' is the wordplay.
'raised' says the letters should be written backwards (going up in a down clue).
'in' indicates a hidden word.
'sala' can be found hidden inside 'crossalaght'.
'sala' written backwards gives 'ALAS'.
(Other definitions for alas that I've seen before include "Proper, respectable" , "I'm sorry to say" , "Cry of regret" , "Expression of regret" , "Regrettably, unfortunately" .)