Unfortunately, we’d Irish setters who control all we do (3,5,7)

I believe the answer is:

the weird sisters

'who control all we do' is the definition.
(the three witches in Shakespeare's Macbeth)

'unfortunately we'd irish setters' is the wordplay.
'unfortunately' is an anagram indicator.
'wed'+'irish'+'setters'='wedirishsetters'
'wedirishsetters' anagrammed gives 'THE WEIRD SISTERS'.

(Another definition for the weird sisters that I've seen is " Scandinavian goddesses".)

I've seen this clue in The Times.

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