Unfriendly to Isaac in foreign lake (10)

I believe the answer is:

antisocial

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'unfriendly' is the definition.
Both the answer and definition are adjectives. Perhaps you can see an association between them that I can't see?

'to isaac in foreign lake' is the wordplay.
'foreign' indicates an anagram (foreign order of the letters).
'lake' becomes 'L' (geographical abbreviation).
'to'+'isaac'+'in'='toisaacin'
'toisaacin' is an anagram of 'antisocia'.
'antisocia'+'l'='ANTISOCIAL'

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(Other definitions for antisocial that I've seen before include "Disinclined to mix" , "withdrawn" , "Disruptive to the community" , "Reluctant to mix" , "Not getting on with others" .)

I've seen this clue in The Telegraph.

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