Unhappy at university place? (5)
I believe the answer is:
upset
'unhappy' is the definition.
(I've seen this before)
'at university place?' is the wordplay.
'at university' becomes 'up'.
'place?' becomes 'set' (setting is a kind of placing**).
'up'+'set'='UPSET'
(Other definitions for upset that I've seen before include "bug" , "Knocked over; unhappy" , "Upheaval" , "Out of sorts" , "Overturn; unhappy" .)