Universal actors Wilder and Pryor hard to abandon (7)
I believe the answer is:
generic
'universal' is the definition.
(thesaurus)
'actors wilder and pryor hard to abandon' is the wordplay.
I cannot really understand how this works, but
'wilder' could be 'gene' (gene wilder) and 'gene' is found within the answer.
The remaining letters 'ric' is a valid word which might be clued in a way I don't see.
This may be the basis of the clue (or it may be nonsense).
Can you help me to learn more?
(Other definitions for generic that I've seen before include "Unspecific" , "cheap drug" , "of a particular type" , "Applicable to any member of a class" , "Non-proprietary (drug)" .)