University seen to spread out and develop (5)
I believe the answer is:
ensue
'develop' is the definition.
(thesaurus)
'university seen to spread out' is the wordplay.
'university' becomes 'U' (abbreviation as in UMass).
'to spread out' indicates an anagram (I've seen 'spreading out' mean this).
'u'+'seen'='useen'
'useen' anagrammed gives 'ENSUE'.
'and' acts as a link.
(Other definitions for ensue that I've seen before include "Happen as a result, follow ( 5)" , "Befall" , "Come along afterwards" , "Leading directly to" , "Transpire" .)