University trained nurse to be hesitant (6)
I believe the answer is:
unsure
'hesitant' is the definition.
(I've seen this in another clue)
'university trained nurse' is the wordplay.
'university' becomes 'U' (abbreviation for university).
'trained' indicates an anagram (to train can mean to grow something into a shape).
'nurse' is an anagram of 'nsure'.
'u'+'nsure'='UNSURE'
'to be' acts as a link.
(Other definitions for unsure that I've seen before include "regarded as somewhat precarious" , "Far from certain" , "Not certain, dubious" , "Not certain or decided" , "Not certain, somewhat confused" .)