Unsure about The Saint (8)
I believe the answer is:
hesitant
'unsure' is the definition.
(thesaurus)
'about the saint' is the wordplay.
'about' is an anagram indicator.
'the'+'saint'='thesaint'
'thesaint' is an anagram of 'HESITANT'.
(Other definitions for hesitant that I've seen before include "Doubtful" , "Diffident" , "Lacking decisiveness" , "Pausing - undecided" , "Demurring" .)