Unusual new route (5)
I believe the answer is:
outre
'unusual' is the definition.
(I've seen this before)
'new route' is the wordplay.
'new' indicates an anagram.
'route' is an anagram of 'OUTRE'.
(Other definitions for outre that I've seen before include "Not abiding by what is proper" , "Unseemly route taken in France" , "Weird" , "Disturbingly unusual" , "Extravagant - fantastic" .)