Unusual of female to strike (7)
I believe the answer is:
offbeat
'unusual' is the definition.
(thesaurus)
'of female to strike' is the wordplay.
'female' becomes 'f' (abbreviation).
'to strike' becomes 'beat' (I've seen this before).
'of'+'f'+'beat'='OFFBEAT'
(Other definitions for offbeat that I've seen before include "Strikingly unconventional" , "Odd, unconventional" , "Unusual, not ordinary - or rhythmic" , "Kooky" , "Wacky; syncopated" .)