Unusually gifted, one's always on the move (6)
I believe the answer is:
fidget
'one's always on the move' is the definition.
(someone who fidgets or moves)
'unusually gifted' is the wordplay.
'unusually' is an anagram indicator.
'gifted' with letters rearranged gives 'FIDGET'.
(Other definitions for fidget that I've seen before include "Make nervous restless movements" , "Betray boredom, impatience" , "Make small nervous movements" , "Make small restless movements with hands" , "Make small movements through nervousness or impatience" .)