Up and about needing a wash (5)
I believe the answer is:
awake
'up and about' is the definition.
(I've seen this in another clue)
'a wash' is the wordplay.
'wash' becomes 'wake' (I've seen this before).
'a'+'wake'='AWAKE'
'needing' acts as a link.
(Other definitions for awake that I've seen before include "Make active again" , "Conscious and (usually) open-eyed" , "Not asleep" , "Cease sleeping" , "Come to" .)