Up to carrying cross? It’ll repel evil (6)
I believe the answer is:
amulet
'it'll repel evil' is the definition.
I can't judge whether this definition defines the answer.
'up to carrying cross?' is the wordplay.
'up to' becomes 'at' (I am not sure about this - if you are sure you should give a lot more credence to this answer).
'carrying' indicates putting letters inside.
'cross?' becomes 'mule' (a mule is a cross of a donkey and a horse).
'at' enclosing 'mule' is 'AMULET'.
Can you help me to learn more?
(Other definitions for amulet that I've seen before include "Charm worn against bad luck" , "Charm to protect from evil" , "Charm warding off evil" , "Ornament worn as a charm against evil" , "Magical charm" .)