Uproar with rubbish around capital of Italy (4)
I believe the answer is:
riot
'uproar' is the definition.
(both can mean a disturbance or commotion)
'rubbish around capital of italy' is the wordplay.
'rubbish' becomes 'rot' (both can mean nonsense).
'around' is an insertion indicator.
'capital of' says to take the initial letters.
The first letter of 'italy' is 'i'.
'rot' placed around 'i' is 'RIOT'.
'with' is the link.
(Other definitions for riot that I've seen before include "unrestrained revelry" , "Run amok" , "Take to the streets" , "Wild disturbance by crowd of people" , "Rampage" .)