Upset and angered perhaps (7)
I believe the answer is:
derange
'upset' is the definition.
(deranging is a kind of upseting)
'angered perhaps' is the wordplay.
'perhaps' is an anagram indicator.
'angered' anagrammed gives 'DERANGE'.
'and' is the link.
(Other definitions for derange that I've seen before include "Craze" , "Upset" , "Unhinge" , "Make insane" , "Remove from order" .)