Upset drink taking one's time (10)
I believe the answer is:
distraught
'upset' is the definition.
(thesaurus)
'drink taking one's time' is the wordplay.
'drink' becomes 'draught' (draught is a kind of drink**).
'taking' indicates putting letters inside.
'one's' becomes 'is' (roman numeral).
'time' becomes 't'.
'is'+'t'='ist'
'draught' going around 'ist' is 'DISTRAUGHT'.
(Other definitions for distraught that I've seen before include "wild" , "Greatly agitated in mind - hits at drug (anag)" , "Grief-stricken" , "Very worried and upset" , "crazy" .)