Upset from flying (3,3)

I believe the answer is:

jet lag

(Other definitions for jet lag that I've seen before include "Fatigue caused by flying to a distant time zone" , "Bad effect of air travel" , "Disorientation caused by long-distance air travel" , "Air traveller's tiredness" , "Effect of long distance journey" .)

I've seen this clue in The Times.

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