Upset, in tears - less pleasant (7)
I believe the answer is:
nastier
'less pleasant' is the definition.
(I've seen this in another clue)
'upset in tears' is the wordplay.
'upset' indicates anagramming the letters.
'in'+'tears'='intears'
'intears' with letters rearranged gives 'NASTIER'.
(Other definitions for nastier that I've seen before include "Less nice" , "Less pleasant" , "More damaging" , "Retsina (anag) -- not so nice" , "More horrid" .)