Upset Seddon’s eccentricity (7)
I believe the answer is:
oddness
'eccentricity' is the definition.
(oddness is a kind of eccentricity)
'upset seddon's' is the wordplay.
'upset' indicates anagramming the letters.
'seddons' is an anagram of 'ODDNESS'.
(Other definitions for oddness that I've seen before include "Peculiarity characteristic" , "Peculiar quality" , "It isn't even" , "Eccentricity" , "a peculiarity of character" .)