Upset, shake (6)
I believe the answer is:
rattle
I believe this clue is a double definition.
'upset' is the first definition.
(I know that upset can be written as rattle)
'shake' is the second definition.
(I know that rattle is a kind of shake)
(Other definitions for rattle that I've seen before include "Gurgling sound in throat" , "American snake" , "Disconcert - conductor, Simon" , "Noisy baby's toy" , "Trivial talk" .)