Upsets son with alcoholic drinks (6)
I believe the answer is:
shocks
'upsets' is the definition.
(shock can mean to upset or disturb)
'son with alcoholic drinks' is the wordplay.
'son' becomes 's' (genealogical abbreviation for son).
'with' means one lot of letters go next to another.
'alcoholic drinks' becomes 'hocks' (hock is a type of wine).
's'+'hocks'='SHOCKS'
(Other definitions for shocks that I've seen before include "'Stuns, jolts (6)'" , "Appals" , "Surprises, sometimes electrical" , "Effects of charges of electricity" , "Jolts, jars" .)